Bitcoin DeFi grows with Wormhole’s cross-chain integration on Mezo

Mezo Network Overview - August 5, 2025

Aug 05, 2025

Welcome to the monthly Mezo Network Overview. Every month, we’re diving into the Mezo ecosystem developments to help you get up to speed on the network’s latest updates, metrics, ecosystem developments and more.All in one place.

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Mezo Metrics

Total value locked (TVL): $69.29M
MUSD supply: $3.38M
Users (total addresses): 11.3K

The metrics are accurate at the time of publication.

Mezo’s path to making bitcoin as productive as cash

Historically, bitcoin has been seen as either a store of value or investable asset, similar to how gold is in the traditional finance world. But, bitcoin has been limited in having utility across staking, lending or DeFi. Although bitcoin is a multi-trillion dollar asset, its limited access to DeFi meant users couldn’t access their wealth unless they were willing to sell their bitcoin.

With Mezo, the network aims to become the place for people who want to use their bitcoin in order to buy a home, car, or even groceries. By offering options like a bitcoin loan, Mezo lets users unlock the value of their holdings while still keeping exposure to bitcoin’s upside.

“We don't wanna replay Ethereum, this isn't Pumpfun,” Thesis CEO and Mezo Founder Matt Luongo said during the Mezo Quarterly Webinar with Token Relations. “We're looking to help larger players and exchange traded products (ETP) find yield, but also get access to their equity.”

Mezo is giving investors the opportunity to have more buying power with their bitcoin, but without having to give up their holdings. It’s “ giving holders the opportunity to be financially productive,” Luongo noted. “Do what rich people do, which is to borrow against your assets so you don’t have to sell something that you think is gonna go up - and to create more wealth, more widely.”

Aside from bitcoin, stablecoins have also gained traction for providing crypto users access to their wealth in a decentralized manner.

So for Mezo, it combined the ethos of bitcoin with the stability of stablecoins to create an asset that can be used in everyday life. “ A friend of mine who’s been sitting on bitcoin for years, was able to use Mezo’s stablecoin, MUSD, borrowed against his holdings and was able to buy a set of groceries,” Mezo Founding Contributor Harsharn Singh said. “If I can live my life using bitcoin, I know there won’t be as much censorship compared to USDC or USDT.”

These DeFi and real life applications that Mezo’s stablecoin offers plays a huge role in its contributions to the BTCfi ecosystem. However, limiting these use cases to just the Mezo network isn’t the end goal, the team shared. Through its partnership with Wormhole, Mezo hopes to extend these offerings to users on Ethereum as well.

Extending capabilities to Ethereum and beyond

On Monday, Mezo announced a partnership with Wormhole to enable cross-chain capabilities for MUSD. Through Wormhole’s Native Token Transfers (NTT) standard, MUSD can move across Mezo and Ethereum. This allows MUSD to be minted, swapped or bridged across Ethereum-based protocols, unlocking new yield-generation opportunities for bitcoin-backed pairs like ETH/MUSD or USDC/MUSD within the Ethereum ecosystem.

Since Ethereum is the largest network by TVL at $80 billion, with more than 1,561 DeFi protocols, this integration enables bitcoin holders the ability to leverage their assets across the biggest DeFi ecosystem. The integration into Ethereum lets bitcoin holders on Mezo access new financial opportunities like earning returns through liquidity pools.

Additionally, Mezo’s partnership with Wormhole strengthens the broader infrastructure for cross-chain DeFi as it creates a secure and efficient bridge for bitcoin-backed assets and enhances accessibility and utility for users worldwide.

Bridge MUSD to Ethereum

Expanding the ecosystem

Mezo launched Pools, a liquidity provision feature designed for DeFi users seeking yield opportunities within the BTCfi ecosystem
Supernormal Foundation announced its community-driven, non-profit designed to foster ecosystem growth and provide Mezo dApps guidance
Mezo introduced its MUSD Vault, a way for users to earn automated, sustainable yield on MUSD
- Upshift deployed support for the MUSD Vault with up to 30% APY

Get active in the network

Want to dive deeper into the Mezo ecosystem?

Rewards for tBTC are live on Mezo with up to $80K available until August 31
Applications for Mezo’s Alpha Builder Program are open for projects looking to integrate MUSD
Use MUSD to unlock digital gift cards through Bitrefill, a platform that lets users shop with crypto on Amazon, Apple or Uber
Donate MUSD to support SheFi’s mission of empowering women to build on web3
Support open source Bitcoin development by donating MUSD to Brink’s nonprofit

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This information is for entertainment purposes only. It should not be considered financial advice, nor should it be used to make investment decisions. Cryptocurrencies are high risk and you should consult a financial professional before making any financial decisions. Make sure you do your own research.